ESOMEPRAZOLE — Side Effects and Special Considerations

Home Forums Acid Reducers Esomeprazole ESOMEPRAZOLE — Side Effects and Special Considerations

This topic contains 2 replies, has 2 voices, and was last updated by  MJ 5 months, 1 week ago.

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  • #422

    MJ
    Moderator

    Esomeprazole is non-drowsy, but can cause other side effect listed below, but is not limited to:

    COMMON SIDE EFFECTS

    *for Adult:
    1. headache
    2. diarrhea
    3. nausea
    4. flatulence (passing gas)
    5. stomach pain
    6. constipation
    7. dry mouth

    *for Children
    1. headache
    2. diarrhea
    3. nausea
    4. flatulence (passing gas)
    5. stomach pain
    6. constipation
    7. dry mouth
    8. regurgitation (burping up food)
    9. increased breathing rate

    Mild side effects may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, consult to your doctor.

    SERIOUS SIDE EFFECTS
    *Severe diarrhea characterized by:
    1. watery stool
    2. stomach pain
    3. fever that doesn’t go away

    *Bone fractures

    *Atrophic gastritis characterized by:
    1. stomach pain
    2. nausea
    3. vomiting
    4. weight loss

    *Low magnesium levels characterized by:
    1. seizures
    2. dizziness
    3. abnormal or fast heart rate
    4. jitteriness
    5. tremors (jerking movements or shaking)
    6. muscle weakness
    7. spasms in your hands and feet
    8. cramps or muscle aches
    9. spasm of your voice box

    *Vitamin B-12 deficiency characterized by:
    1. nervousness
    2. inflammation of a nerve which causes nerve pain and tingling
    3. numbness and tingling in your hands and feet
    4. poor muscular coordination
    5. menstrual bleeding that’s heavier than normal

    SPECIAL CONSIDERATIONS

    1. Esomeprazole must not be taken with the following drugs:
    a. Clopidogrel
    b. Diazepam
    c. Warfarin
    d. Cilostazol
    e. Digoxin
    f. Methotrexate
    g. Saquinavir
    h. Tacrolimus
    i. Voriconazole
    j. Clarithromycin
    k. Atazanavir
    l. Nelfinavir
    m. Mycophenolate mofetil
    n. Rifampin

    2. Warning for people with the following health conditions:
    a. severe liver problems
    b. low magnesium blood levels
    c. vitamin B-12 deficiency
    d. osteoporosis
    e. people with plans to have neuroendocrine tumor test

    3. Esomeprazole magnesium may pass into breast milk and may cause side effects in a child who is breastfed. Talk to your doctor if you breastfeed your child.

    #509

    luisedwards112
    Participant

    What are the interactions when taking Nexium with Plavix?

    #510

    MJ
    Moderator

    Hello, there is a major drug interaction between Plavix (clopidogrel) and Nexium (esomeprazole).
    Using these two together is generally to be avoided since co-administration of clopidogrel with a proton pump inhibitors (PPIs) may reduce the cardio-protective effects of clopidogrel. Thus, for those treated with clopidogrel, H2-receptor antagonists or antacids such as famotidine, ranitidine, or cimetidine should be considered whenever possible.

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