MEMANTINE — Side Effects and Special Considerations

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    Mamantine side effects include, but is not limited to:

    1. dizziness
    2. confusion
    3. aggression
    4. depression
    5. headache
    6. sleepiness
    7. diarrhea
    8. constipation
    9. nausea
    10. vomiting
    11. weight gain
    12. pain anywhere in your body, especially your back
    13. cough

    Mild side effects may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, consult with your doctor.

    1. shortness of breath
    2. hallucination (seeing things or hearing voices that do not exist)

    Call your doctor immediately or get emergency medical help if you experience serious side effects.

    1. Extended-release capsules should be swallowed whole; do not chew, divide, or crush them. If you are unable to swallow it whole, you can carefully open a capsule and sprinkle the contents on a spoonful of applesauce. Swallow this mixture immediately without chewing it. Do not save this mixture to use at a later time.

    2. Continue to take memantine even if you feel well. Do not stop taking memantine without talking to your doctor.

    3. Inform your doctor if you have any food or drug allergy.

    4. Before using this drug, inform your doctor about your medical history, especially of:
    a. kidney problems
    b. severe urinary tract infections
    c. recent dietary change (from a high-protein diet to a vegetarian diet).

    5. This medication may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. You should also limit alcoholic beverages.

    6. During pregnancy, this medication should be used only when clearly needed. Thus. risk and benefits must be discussed with your doctor. Discussion must also be done before breast-feeding a child.

    7. Some of the products that may interact with this drug include:
    a. carbonic anhydrase inhibitors (such as acetazolamide, methazolamide)
    b. sodium bicarbonate


    Hi, does memantine raise blood pressure? My uncle’s blood pressure seem to have been elevated a bit since he started this medication. Could it have been caused by the medication?


    Memantine may cause increased blood pressure. Therefore, if your uncle has any heart problem, and with the elevation in his blood pressure, it would be best to consult with his doctor so that he will be aware of how the medication is affecting his medical condition. His doctor will be able to assess the if a change in dosing is needed or whether any special monitoring will be necessary.

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